LI Glycoscience Group
PEER-REVIEWED PUBLICATIONS
Year 2024
82. Shumin Bao, MohammadHossein Shabahang, Tangliang Shen, Guitao Bai, Lei Li*. Enzymatic Synthesis of Disialyllacto-N-Tetraose
(DSLNT) and Related Human Milk Oligosaccharides Reveals Broad Siglec Recognition to the Atypical Neu5Acα2-6GlcNAc Motif.
Angew Chem Int Ed, 2024, DOI: 10.1002/anie.202411863.
81. Madhusudhan R. Gadi, Jinghua Han, Tangliang Shen, Shuquan Fan, Zhongying Xiao, Lei Li*. Divergent Synthesis of Amino Acid-
Linked O-GalNAc Glycan Core Structures. Nat Protoc, 2024, DOI: 10.1038/s41596-024-01051-6. Featured Protocol of the Week.
80. Minhui Guan, Thomas DeLiberto, Aijing Feng, Jieze Zhang, Tao Li, Shuaishuai Wang, Lei Li, Mary Killian, Beatriz Praena, Emily
Giri, Shelagh Deliberto, Jun Hang, Alicia Olivier, Mia Torchetti, Yizhi Tao, Colin Parrish, Xiu-feng Wan. Neu5Gc binding loss of
subtype H7 influenza A virus facilitates adaptation to gallinaceous poultry following transmission from waterbirds. J Virol, 2024,
79. Yinshuang Li, Yi Li, Yuxi Guo, Congcong Chen, Lin Yang, Qian Jiang, Peixue Ling, Shuaishuai Wang*, Lei Li*, Junqiang Fang*.
Enzymatic modular synthesis of asymmetrically branched human milk oligosaccharides. Carbohydr Polym, 2024, 333, 121908.
78. Cheng Gao, Feng Wen, Minhui Guan, Bijaya Hatuwal, Lei Li, Beatriz Praena, Cynthia Tang, Jieze Zhang, Feng Luo, Hang Xie,
Richard Webby, Yizhi Tao, Xiu-Feng Wan. MAIVeSS: Streamlined selection of antigenically matched, high-yield viruses for seasonal
influenza vaccine production. Nat Commun, 2024, 15, 1128.
Year 2023
77. Shuang Li, Shuaishuai Wang, Jingyao Qu, Jingjun Han, Lin Yang, Yi Li, Lei Li, Qingwen Jia, Congcong Chen, Peixue Lin &
Junqiang Fang. Programmable one cycle–one disaccharide unit modular synthesis of hyaluronan and chondroitin hybrid glycans.
Green Chem, 2023, 23, 2021-2027.
76. Madhusudhan Reddy Gadi, Congcong Chen, Shumin Bao, Shuaishuai Wang, Yuxi Guo, Jinghua Han, Weidong Xiao & Lei Li.
Convergent chemoenzymatic synthesis of O-GalNAc rare cores 5, 7, 8 and their sialylated forms. Chem Sci, 2023, 14, 1837.
75. Tin Long Wong, Brian P. Mooney, Gustavo J. Cavallero, Minhui Guan, Lei Li, Joseph Zaia & Xiu-Feng Wan. Glycoproteomic
Analyses of Influenza A Viruses Using timsTOF Pro MS. J Proteome Res, 2023, 22, 62.
74. Junping Zhang, Matthew Chrzanowski, Dylan A Frabutt, Anh K Lam, Patrick L Mulcrone, Lei Li, Barbara A Konkle, Carol H Miao &
Weidong Xiao. Cryptic resolution sites in the vector plasmid lead to the heterogeneities in the rAAV vectors. J Med Virol, 2023, 95,
Year 2022
73. Anh K. Lam, Junping Zhang, Dylan Frabutt, Patrick L. Mulcrone, Lei Li, Lifan Zeng, Roland W. Herzog & Weidong Xiao. Fast and
high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS. Mol Ther Methods
72. Minhui Guan, Alicia K. Olivier, Xiaotong Lu, William Epperson, Xiaojian Zhang, Lei Zhong, Kaitlyn Waters, Nataly Mamaliger, Lei Li,
Feng Wen, Yizhi J. Tao, Thomas J. DeLiberto & Xiu-Feng Wan. The Sialyl Lewis X Glycan Receptor Facilitates Infection of Subtype
H7 Avian Influenza A Viruses. J Virol, 2022, 96, e0134422.
71. Xuefeng Cao, Shuaishuai Wang, Madhusudhan Reddy Gadi, Ding Liu, Peng G. Wang, Xiu-Feng Wan, Jian Zhang, Xi Chen, Lauren
E. Pepi, Parastoo Azadi & Lei Li. Systematic synthesis of bisected N-glycans and unique recognitions by glycan-binding proteins.
Chem Sci, 2022, 13, 7644-7656.
70. Amber Vander Kooi, Shuaishuai Wang, Meng-Ni Fan, Alex Chen, Junping Zhang, Chun-Yu Chen, Xiaohe Cai, Barbara A Konkle,
Weidong Xiao, Lei Li & Carol H Miao. Influence of N-glycosylation in the A and C domains on the immunogenicity of factor VIII.
Blood Adv, 2022, 2022, 6, 4271–4282.
69. Edwin E. Escobar, Shuaishuai Wang, Rupanjan Goswami, Michael B. Lanzillotti, Lei Li, Jason S. McLellan & Jennifer S. Brodbelt.
Analysis of Viral Spike Protein N-Glycosylation Using Ultraviolet Photodissociation Mass Spectrometry. Anal Chem, 2022, 94, 15,
68. Qing Zhang, Shuaishuai Wang, Zhonghua Li, Yi Lasanajak, Lei Li & Xuezheng Song. Regeneration of Free Reducing Glycans from
Reductive Amination-Tagged Glycans by Oxone. J Org Chem, 2022, 87, 3736.
Year 2021
67. Xuan Fu, Madhusudhan Reddy Gadi, Shuaishuai Wang, Jinghua Han, Ding Liu, Xi Chen, Jun Yin* & Lei Li* General Tolerance of
Galactosyltransferases toward UDP-galactosamine Expands Their Synthetic Capability. Angew Chem Int Ed, 2021, 60, 26555.
66. Anh Kim Lam, Dylan A Frabutt, Lei Li & Weidong Xiao. Chemical Modification of the Capsid for Redirecting and Improving the
Efficacy of AAV Vectors. Hum Gene Ther, 2021, 32, 1433.
65. Hai Yu, Madhusudhan Reddy Gadi, Yuanyuan Bai, Libo Zhang, Lei Li, Jun Yin, Peng G. Wang & Xi Chen. Chemoenzymatic Total
Synthesis of GM3 Gangliosides Containing Different Sialic Acid Forms and Various Fatty Acyl Chains. J Org Chem, 2021, 868672.
64. Ding Liu, Shuaishuai Wang, Junping Zhang, Weidong Xiao, Carol H Miao, Barbara A Konkle, Xiu-Feng Wan & Lei Li*. Site-specific
N-and O-glycosylation Analysis of Human Plasma Fibronectin. Front Chem, 2021, 9, 415.
63. Shuaishuai Wang, Chongcong Chen, Madhusudhan Reddy Gadi, Varma Saikam, Ding Liu, He Zhu, Roni Bollag, Kebin Liu, Xi
Chen, Fengshan Wang, Peng George Wang*, Peixue Ling*, Wanyi Guan* & Lei Li*. Chemoenzymatic modular assembly of O-
GalNAc glycans for functional glycomics. Nat Commun, 2021, 12, 3573.
62. Shuaishuai Wang, Chongcong Chen, Minhui Guan, Xiu-Feng Wan & Lei Li*. Terminal epitope-dependent branch preference of
Siglecs towards N-glycans. Front Mol Biosci, 2021, 8, 645999.
61. Gao-Lan Zhang, Madhusudhan Reddy Gadi*, Xikai Cui, Ding Liu, Jiabin Zhang, Varma Saikam, Christopher Gibbons, Peng G.
Wang & Lei Li*. Protecting-group-free S-glycosylation towards thioglycosides and thioglycopeptides in water.
Green Chem, 2021, 23, 2907-2912. 2021 HOT Green Chemistry article, Inside Back Cover
60. Shuaishuai Wang, Ding Liu, Jingyao Qu, He Zhu, Congcong Chen, Christopher Gibbons, Harmon Greenway, Peng Wang,
Roni J. Bollag, Kebin Liu & Lei Li*. Streamlined Subclass-Specific Absolute Quantification of Serum IgG Glycopeptides
Using Synthetic Isotope-Labeled Standards. Anal Chem, 2021, 93, 4449–4455.
Year 2020
59. Xuefeng Wang, Richard Y Fu, Chong Li, Chun-Yu Chen, Jenni Firrman, Barbara A Konkle, Junping Zhang, Lei Li, Weidong Xiao,
Mortimer Poncz & Carol H Miao. Enhancing therapeutic efficacy of in vivo platelet-targeted gene therapy in hemophilia A mice.
Blood Adv, 2020, 4, 5722-5734.
58. Ding Liu, Maureen Meister, Shiying Zhang, Chi-In Vong, Shuaishuai Wang, Ruixie Fang, Lei Li, Peng George Wang, Pierre
Massion & Xiangming Ji. Identification of lipid biomarker from serum in patients with chronic obstructive pulmonary disease.
57. Cheng Ma, Ding Liu, Dong Li, Junping Zhang, Xiao-Qian Xu, He Zhu, Xiufeng Wan, Carol H. Miao, Barbara A. Konkle, Philip
Onigman, Weidong Xiao* & Lei Li*. Comprehensive N- and O-glycosylation mapping of human coagulation factor V.
J Thromb Haemost, 2020, 18, 1884-1892. Editor's Highlight and Cover Gallery
56. Ding Liu, Jiabin Zhang, He Zhu, Samuel Polizzi, Michael Jones, Lei Li, Peng Wang, Wei Huang & Cheng Ma. Enzymatic
depolymerization of Streptococcus pneumoniae type 8 polysaccharide. Carbohydr Res, 2020, 495, 108024.
55. Congcong Chen, Shuaishuai Wang, Madhusudhan Reddy Gadi, He Zhu Fei Liu, Chang-Cheng Liu, Lei Li*, Fengshan Wang*,
Peixue Ling* & Hongzhi Cao*. Enzymatic modular synthesis and microarray assay of poly-N-acetyllactosamine derivatives.
Chem Commun, 2020, 56, 7549-7552. Cover Story
54. Jingyao Qu, Cheng Ma, Xiao-Qian Xu, Min Xiao, Junping Zhang, Dong Li, Barbara Konkle, Carol Miao, Lei Li* & Weidong Xiao*.
Comparative glycosylation mapping of recombinant and plasma-derived human factor VIII. PLoS One, 2020, 15, e0233576.
53. He Zhu, Shuaishuai Wang, Ding Liu, Lang Ding, Congcong Chen, Yunpeng Liu Zhigang Wu, RoniBollag, Kebin Liu, Jun Yin, Cheng
Ma, Lei Li* & Peng George Wang*. Identifying sialylation linkages at the glycopeptide level by glycosyltransferase labeling assisted
mass spectrometry (GLAMS). Anal Chem, 2020, 92, 6297-6303.
52. Lei Li*, Wanyi Guan, Gaolan Zhang, Zhigang Wu, Hai Yu, Xi Chen & Peng George Wang. Microarray analyses of closely related
glycoforms reveal different accessibilities of glycan determinants on N-glycan branches. Glycobiology, 2020, 30, 334-345.
51. Zhongrui Ma, Gaolan Zhang, Madhusudhan Reddy Gadi, Yuxi Guo, Peng Wang & Lei Li*. Clostridioides difficile cd2775 encodes
a unique mannosyl-1-phosphotransferase for polysaccharide II biosynthesis. ACS Infect Dis, 2020, 6, 680-686.
2006-2019
50. Ke Qu, Shukkoor M. Kondengaden, Jian Li, Xuewei Wang, Michael D. Sevilla, Lei Li & Xiangqun Zeng. Carbohydrate-
functionalized polythiophene biointerface: design, fabrication, characterization and application for protein analysis. Appl Surf Sci,
49. Zhongrui Ma, Huangjie Zhang, Lei Li, Min Chen & Peng G. Wang. Direct cloning of Escherichia coli O-antigen gene cluster and
its application for in vivo production of glycoconjugate vaccine. ACS Infect Dis, 2019, 5, 74-78.
48. Shuaishuai Wang, Qing Zhang, Congcong Chen, Yuxi Guo, Madhusudhan Reddy Gadi, Jin Yu, Ulrika Westerlind, Yunpeng Liu,
Xuefeng Cao, Peng G. Wang* & Lei Li*. Facile chemoenzymatic synthesis of O-mannosyl glycans. Angew Chem Int Ed, 2018, 57,
47. Feng Wen, Sherry Blackmon, Alicia K. Olivier, Lei Li, Minhui Guan, Hailiang Sun, Peng G. Wang & Xiu-Feng Wan. Mutation W222L
at the receptor binding site of hemagglutinin could facilitate viral adaption from equine influenza A(H3N8) virus to dogs. J Virol,
46. Sharad Purohit, Wanyi Guan, Xuezheng Song, Jing Song, Yanna Tian, Tiehai Li, Lei Li, Ashok Sharma, Boying Dun, Richard D.
Cummings, Peng G. Wang & Jin-Xiong She. Multiplex glycan bead array: a high throughput and high content platform for glycan
binding proteins. Nat Commun, 2018, 9, 258.
45. Feng Wen, Lei Li, Meng-Jung Chiang, Nan Zhao, Hang Xie, Jim Cooley, Richard Webby, Peng G. Wang & Xiu-Feng Wan.
A Y161F hemagglutinin substitution increases antigenic thermostability and improves yields of 2009 H1N1 influenza A virus in cells.
44. Angie D. Calderon, Jun Zhou, Wanyi Guan, Zhigang Wu, Yuxi Guo, Jing Bai, Qing Li, Peng G. Wang, Junqiang Fang* & Lei Li*.
An enzymatic strategy to asymmetrically branched N-glycans. Org Biomol Chem, 2017, 15, 7258-7262.
43. Zhigang Wu, Yunpeng Liu, Lei Li, Xiu-Feng Wan, He Zhu, Yuxi Guo, Mohui Wei, Wanyi Guan & Peng G. Wang. Decoding glycan
protein interactions by a new class of asymmetric N-glycans. Org Biomol Chem, 2017, 15, 8946-8951.
42. Hai Yu, Yanhong Li, Zhigang Wu, Lei Li, Jie Zeng, Chao Zhao, Yijing Wu, Nova Tasnima, Jing Wang, Huaide Liu, Madhusudhan
Reddy Gadi, Wanyi Guan, Peng G. Wang & Xi Chen. Helicobacter pylori a1–3/4-fucosyltransferase (Hp3/4FT)-catalyzed one-pot
multienzyme (OPME) synthesis of Lewis antigens and human milk fucosides. Chem Commun, 2017, 53, 11012-11015.
41. Kuan Jiang, He Zhu, Lei Li, Yuxi Guo, Ebtesam Gashash, Cheng Ma, Xiaolin Sunc, Jing Li, Lianwen Zhang & Peng G. Wang.
Sialic acid linkage-specific permethylation for improved profiling of protein glycosylation by MALDI-TOF MS. Anal Chim Acta,
40. Hailiang Sun, Bryan S Kaplan, Minhui Guan, Guihong Zhang, Jianqiang Ye, Li-Ping Long, Sherry Blackmon, Chun-Kai Yang,
Meng-Jung Chiang, Hang Xie, Nan Zhao, Jim Cooley, David F Smith, Ming Liao, Carol Cardona, Lei Li, George Peng Wang,
Richard Webby & Xiu-Feng Wan. Pathogenicity and transmission of a swine influenza A(H6N6) virus. Emerg Microbes Infec,
39. Angie D. Calderon, Lei Li & Peng G. Wang. FUT8: from biochemistry to synthesis of core-fucosylated N-glycans. Pure Appl Chem,
38. Lei Li, Robert L. Woodward, Weiqing Han, Jingyao Qu, Jing Song, Cheng Ma & Peng G. Wang. Chemoenzymatic synthesis of
bacterial polysaccharide repeating unit-pyrophosphate-undecaprenyl and analogues. Nat Protoc, 2016, 11, 1280-1298.
37. Angie D. Calderon, Yunpeng Liu, Xu Li, Xuan Wang, Xi Chen, Lei Li* & Peng G. Wang*. Substrate specificity of FUT8 and
chemoenzymatic synthesis of core-fucosylated asymmetric N-glycans. Org Biomol Chem, 2016, 14, 4027-4031.
36. Zhigang Wu, Guohui Zhao, Tiehai Li, Jingyao Qu, Wanyi Guan, Jiajia Wang, Cheng Ma, Xu Li, Wei Zhao, Peng G. Wang* & Lei Li*.
Biochemical characterization of an a1,2-colitosyltransferase from Escherichia coli O55:H7. Glycobiology, 2016, 26, 493-500.
35. Zhigang Wu, Kuan Jiang, Hailiang Zhu, Cheng Ma, Zaikuan Yu, Lei Li, Wanyi Guan, Yunpeng Liu, He Zhu, Yanyi Chen, Shanshan
Li, Jing Li, Jiansong Cheng, Lianwen Zhang & Peng G. Wang. Site-directed glycosylation of peptide/protein with homogeneous
O‑linked eukaryotic N‑Glycans. Bioconjugate Chem, 2016, 27, 1972-1975.
34. Yunpeng Liu, Liuqing Wen, Lei Li, Madhusudhan Reddy Gadi, Wanyi Guan, Kenneth Huang, Zhongying Xiao, Mohui Wei, Cheng
Ma, Qing Zhang, Hai Yu, Xi Chen, Peng G. Wang & Junqiang Feng. A general chemoenzymatic strategy for the synthesis of
glycosphingolipids. Eur J Org Chem, 2016, 4315-4320.
33. Zhigang Wu, Yunpeng Liu, Cheng Ma, Lei Li, Jing Bai, Lauren Byrd-Leotis, Yi Lasanajak, Yuxi Guo, Liuqing Wen, He Zhu, Jing
Song, Yanhong Liu, David A. Steinhauer, David F. Smith, Baohua Zhao, Xi Chen, Wanyi Guan & Peng G. Wang. Identification of
the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes.
Org Biomol Chem, 2016, 14, 11106-11116.
32. Zhongying Xiao, Yuxi Guo, Yunpeng Liu, Lei Li, Qing Zhang, Liuqing Wen, Xuan Wang, Shukkoor Muhammed Kondengaden,
Zhigang Wu, Jun Zhou, Xuefeng Xao, Xu Li, Cheng Ma & Peng G. Wang. Chemoenzymatic synthesis of a library of human milk
oligosaccharides. J Org Chem, 2016, 81, 5851-5865.
31. Cheng Ma, Jingyao Qu, Xu Li, Yinyuan Zhao, Lei Li, Cong Xiao, Garett Edmunds, Ebtesam Gashash, Jing Song & Peng G. Wang.
Improvement of core-fucosylated glycoproteome coverage via alternating HCD and ETD fragmentation. J Proteomics, 2016, 146,
30. Jiajia Wang, Xiaomin Wang, Yunyan Zhao, Xiaoyao Ma, Yue Wan, Zhongwei Chen, Hao Chen, Hao Gan, Jing Li, Lei Li, Peng G.
Wang & Wei Zhao. Synthesis and biological evaluation of D-gluconhydroximo-1,5-lactam and its oxime-substituted derivatives as
pharmacological chaperones for the treatment of Gaucher. MedChemComm, 2016, 7, 365-370.
29. Lei Li, Yunpeng Liu, Cheng Ma, Jingyao Qu, Angie D. Calderon, Baolin Qu, Na Wei, Xuan Wang, Yuxi Guo, Zhongying Xiao, Jing
Song, Go Sugiarto, Yanhong Liu, Hai Yu, Xi Chen & Peng G. Wang. Efficient chemoenzymatic synthesis of an N-glycan isomer
library. Chem Sci, 2015, 6, 5652-5661.
28. Lei Li*, Yonghui Liu, Tiehai Li, Wenjun Wang, Zaikuan Yu, Cheng Ma, Jingyao Qu, Wei Zhao, Xi Chen & Peng G. Wang*. Efficient
chemoenzymatic synthesis of novel galacto-N-biose derivatives and their sialylated forms. Chem Commun, 2015, 51, 10310-10313.
27. Yuxi Guo, Junqiang Fang, Tiehai Li, Xu Li, Cheng Ma, Xuan Wang, Peng G. Wang* & Lei Li*. Comparing substrate specificity of
two UDP-sugar pyrophosphorylases and efficient one-pot enzymatic synthesis of UDP-GlcA and UDP-GalA. Carbohydr Res, 2015,
26. Cheng Ma, Jingyao Qu, Jeffrey Meisner, Xinyuan Zhao, Xu Li, Zhigang Wu, Hailiang Zhu, Zaikuan Yu, Lei Li, Yuxi Guo, Jing Song
& Peng G. Wang. Convenient and precise strategy for mapping N-glycosylation sites using microwave-assisted acid hydrolysis and
characteristic ions recognition. Anal Chem, 2015, 87, 7833-7839.
25. Mohui Wei, Zijie Li, Tiehai Li, Baolin Wu, Yunpeng Liu, Jingyao Qu, Xu Li, Lei Li, Li Cai & Peng G. Wang. Transforming flask
reaction into cell-based synthesis: Production of polyhydroxylated molecules via engineered Escherichia coli. ACS Catal, 2015,
24. Musleh M Muthana, Jingyao Qu, Mengyang Xue, Timofey Klyuchnik, Alex Siu, Yanhong Li, Lei Zhang, Hai Yu, Lei Li, Peng G.
Wang & Xi Chen. Improved one-pot multienzyme (OPME) systems for synthesizing UDP-uronic acids and glucuronides.
Chem Commun, 2015, 51, 4595-4598.
23. Guohui Zhao, Baolin Wu, Lei Li & Peng G. Wang. O-antigen polymerase adopts a distributive mechanism for lipopolysaccharide
biosynthesis. Appl Microbiol Biotechnol, 2014, 98, 4075-4081.
22. Tiehai Li, Liuqing Wen, Adriel Williams, Baolin Wu, Lei Li, Jingyao Qu, Jeffrey Meisner, Zhongying Xiao, Junqing Fang & Peng G.
Wang. Chemoenzymatic synthesis of ADP-D-glycero-b-D-manno-heptose and study of the substrate specificity of HldE.
Bioorg Med Chem, 2014, 22, 1139-1147.
21. Lei Li, Yonghui Liu, Yue Wan, Yanhong Li, Xi Chen, Wei Zhao & Peng G. Wang. Efficient enzymatic synthesis of Guanosine 5’-
diphosphate-sugars and derivatives. Org Lett, 2013, 15, 5528-5530.
20. Xiaofeng Ma, Pi Liu, Hui Yan, Hong Sun, Xiaoyan Liu, Feng Zhou, Lei Li, Yi Chen, Musleh M. Muthana, Xi Chen, Peng G. Wang &
Lianwen Zhang. Substrate specificity provides insights into the sugar donor recognition mechanism of O-GlcNAc transferase (OGT).
19. Weiqing Han†, Baolin Wu†, Lei Li†, Guohui Zhao, Robert Woodward, Nicholas Pettit, Li Cai & Peng G. Wang. Defining the function
of E. coli lipopolysaccharide O-antigen ligase WaaL using chemoenzymatically synthesized substrates. J Biol Chem, 2012, 287,
18. Lan Ban†, Nicholas Pettit†, Lei Li†, Andreea Daniela Stuparu, Li Cai, Wenlan Chen, Wanyi Guan, Weiqing Han, Peng G. Wang &
Milan Mrksich. Discovery of glycosyltransferases using carbohydrate arrays and mass spectrometry. Nat Chem Biol, 2012, 8,
17. Lei Li, Yonghui Liu, Wenjun Wang, Jiansong Cheng, Wei Zhao & Peng Wang. A highly efficient galactokinase from Bifidobacterium
infantis with broad substrate specificity. Carbohydr Res, 2012, 355, 35-39.
16. Weiqing Han, Li Cai, Baolin Wu, Lei Li, Zhongying Xiao, Jiansong Cheng & Peng G. Wang. The wciN gene encodes an a-1,3-
galactosyltransferase involved in the biosynthesis of the capsule repeating unit of Streptococcus pneumoniae serotype 6B.
Biochemistry, 2012, 51, 5804-5810.
15. Wenjun Wang, Chen Jin, Lina Guo, Yue Wan, Yu Liu, Xin Wang, Lei Li*, Wei Zhao* & Peng G. Wang*. Preparation of
oligosaccharides with homogenous enzymatic synthesis and solid phase extraction. Chem Commun, 2011, 47, 11240-11242.
14. Guangyan Zhou, Xianwei Liu, Doris Su, Lei Li, Min Xiao & Peng G. Wang. Large scale enzymatic synthesis of oligosaccharides
and a novel purification process. Bioorg Med Chem Lett, 2011, 12, 311-314.
13. Wenjun Wang, Lei Li, Chen Jin, Yujie Niu, Sen Li, Ji Ma, Linfeng Li, Yu Lin, Li Cai, Wei Zhao & Peng G. Wang. Enzymatic synthesis
of a 6-sialyl lactose analogue using a pH-responsive water-soluble polymer support. Bioorg Med Chem Lett, 2011, 21, 5041-5044.
12. Wanyi Guan, Lan Ban, Li Cai, Lei Li, Wenlan Chen, Xianwei Liu, Milan Mrksich & Peng G. Wang. Combining carbochips and mass
spectrometry to study the donor specificity for the Neisseria meningitidis b1,3-N-acetylglucosaminyltransferase LgtA.
Bioorg Med Chem Lett, 2011, 21, 5025-5028.
11. Tiehai Li, Lina Guo, Yan Zhang, Jiajia Wang, Zhonghua Li, Lin Lin, Zhenxing Zhang, Lei Li, Jianping Lin, Wei Zhao, Jing Li & Peng
G. Wang. Design and synthesis of O-GlcNAcase inhibitors via ‘click chemistry’ and biological evaluations. Carbohydr Res, 2011,
10. Robert Woodward†, Wen Yi†, Lei Li†, Guohui Zhao†, Hironobu Eguchi†, Perali R. Sridhar, Hongjie Guo, Jing K. Song, Edwin
Motari, Li Cai, Patrick Kelleher, Xianwei Liu, Weiqing Han, Wenpeng Zhang, Yan Ding, Mei Li & Peng G. Wang. In vitro bacterial
polysaccharide biosynthesis: Defining the functions of Wzy and Wzz. Nat Chem Biol, 2010, 6, 418-423.
9. Lei Li, Robert Woodward, Yan Ding, Xian-wei Liu, Wen Yi, Veer S. Bhatt, Min Chen, Lian-wen Zhang & Peng G. Wang.
Overexpression and topology of bacterial oligosaccharyltransferase PglB. Biochem Biophys Res Commun, 2010, 394, 1069-1074.
8. Jie Yin†, Lei Li†, Neil Shaw, Yang Li, Jing K. Song, Wenpeng Zhang, Chengfeng Xia, Rongguang Zhang, andrzej Joachimiak,
Hou-Cheng Zhang, Lai-Xi Wang, Zhi-Jie Liu & Peng G. Wang. Structural basis and catalytic mechanism for the dual functional
endo-b-N-acetylglucosaminidase A. PLoS One, 2009, 4, e4658.
7. Xian-wei Liu, Chengfeng Xia, Lei Li, Wanyi Guan, Nichols Pettit, Hou-cheng Zhang, Min Chen & Peng G. Wang. Characterization
and synthetic application of a novel b1,3-galactosyltransferase from E. coli O55:H7. Bioorg Med Chem, 2009, 17, 4910-4915.
6. Doris M. Su, Hironobu Eguchi, Wen Yi, Lei Li, Peng G. Wang & Chengfeng Xia. Enzymatic synthesis of tumor-associated
carbohydrate antigen globo-H hexasaccharide. Org Lett, 2008, 10, 1009-1012.
5. Qingjie Wang, Lei Li, Min Chen, Qingsheng Qi & Peng G. Wang. Construction of a novel Pichia pastoris cell-surface display system
based on the cell wall protein Pir1. Curr Microbiol, 2008, 56, 352-357.
4. Qingjie Wang†, Lei Li†, Min Chen, Qingsheng Qi & Peng G. Wang. Construction of novel system for cell surface display of
heterologous proteins in Pichia pastoris. Biotechnol Lett, 2007, 29, 1561-1566.
3. Hongjie Guo, Wen Yi, Lei Li & Peng G. Wang. Three UDP-hexose 4-epimerases with overlapping substrate specificity coexist in
E. coli O86:B7. Biochem Biophys Res Commun, 2007, 356, 604-609.
2. Hongjie Guo†, Lei Li† & Peng G. Wang. Biochemical characterization of UDP-GlcNAc/Glc 4-epimerase from E. coli O86:B7.
Biochemistry, 2006, 45, 13760-13768.
1. Jing Song, Houcheng Zhang, Lei Li, Zishu Bi, Min Chen, Wei Wang, Qingjia Yao, Hongjie Guo, Min Tian, Hanfei Li, Wen Yi &
Peng G. Wang. Enzymatic biosynthesis of oligosaccharides and glycoconjugates. Curr Org Synth, 2006, 3, 159-168.
INVITED BOOKS & CHAPTERS
10. Abdul Rehman, Lei Li & Xiangqun Zeng. Label-Free Biosensors for Studying Carbohydrate-Protein Interactions. Glycan-Based
Cellular Communication: Techniques for Carbohydrate-Protein Interactions (Chapter 6), 2020, 83-117.
9. Synthetic Glycomes, RSC Chemical Biology No. 11, edited by Wanyi Guan, Lei Li & Peng G. Wang, 2019 (Print ISBN: 978-1-78801
-164-8).
8. Shuaishuai Wang, Garrett A. Edmunds, Lei Li, Congcong Chen & Peng G. Wang. Introduction: Glycome and the Glyco-toolbox.
Synthetic Glycomes (Chapter 1), 2019, 1-14.
7. Wanyi Guan, Garrett A. Edmunds, Zhigang Wu & Lei Li. Synthetically Useful Glycosyltransferases for the Access of Mammalian
Glycomes. Synthetic Glycomes (Chapter 3), 2019, 46-82.
6. Lei Li, Wanyi Guan, Zhigang Wu & Peng G. Wang. Chemoenzymatic Synthesis of N-Glycans. Synthetic Glycomes (Chapter 5),
2019, 105-124.
5. Lei Li, Wanyi Guan, Zhigang Wu & Shuaishuai Wang. Current Stage of Commercial Glycan Microarrays. Synthetic Glycomes
(Chapter 19), 2019, 447-460.
4. Xuefeng Cao, Jun Zhou, Yuxi Guo, Yunpeng Liu, Lei Li & Peng G. Wang. Chemoenzymatic Synthesis of N-Glycans. Chemical
Biology of Glycoproteins (Chapter 6), 2017, 188-208.
3. Xian-wei Liu, Lei Li, Hai-tao Gao, Li-jun Dang & Peng G. Wang. Synthesis and modification of carbohydrates via metabolic
pathway engineering in microorganisms. Carbohydrate-Modifying Biocatalysts (Chapter 14), 2011, 549-570.
2. Lei Li, Wen Yi, Wenlan Chen, Robert Woodward, Xian-wei Liu & Peng G. Wang. Production of natural polysaccharides and their
analogues via biopathway engineering. Green Polymer Chemistry: Biocatalysis and Biomaterials, ACS Symposium Series
(Chapter 20). 2010, 1043, 281-297.
1. Weiqing Han, Lei Li, Nicholas Pettit, Wen Yi, Robert Woodward, et al. In vitro reconstitution of Escherichia coli O86 O-antigen
repeating unit. Methods in Molecular Biology (Chapter 7), 2010, 600, 93-110.