LI Glycoscience Group
Principal Investigator
Dr. Lei Li
Assistant Professor
Department of Chemistry
Georgia State University
Office Phone: (404) 413-5073
Office Address: 50 Decatur ST SE
Email:
Dr. Lei Li graduated from Shandong University in China in 2005 with a B.S. degree in Biotechnology. He then received his Ph.D. degree in Microbiology in State Key Laboratory of Microbial Technology at Shandong University in 2010. During the Ph.D. program, he joined Dr. Peng George Wang's group at The Ohio State University as a visiting scholar from 2007 to 2009, where he worked on elucidating the biosynthetic pathway of lipopolysaccharides and synthesis of biomedical-related glycans. He then spent two years at Nankai University as a Postdoctoral Associate, focusing on chemoenzymatic synthesis of complex glycans and sugar nucleotides. In 2013, he joined Dr. Peng George Wang's lab at Georgia State University as Research Scientist I and was promoted to Senior Research Scientist in 2018. He developed independent research programs in microbial glycobiology and glycomics under the support of NIH. In 2020, he joined Department of Chemistry as an Assistant Professor. His research interest includes expedited synthesis of complex carbohydrates and glycoconjugates, glycomics tools (glycan microarray and mass spectrometry) to profile cell-surface glycans and elucidate glycan-protein interactions, as well as carbohydrate-related vaccines and therapeutics against antibiotic-resistant bacteria.
Current Member
Dr. Madhusudhan Reddy Gadi
Research Scientist in Carbohydrate Chemistry
Email:
Dr. Gadi obtained a master’s degree in Chemistry from the University of Hyderabad in 2009 where he worked on the isolation of natural products and chemical synthesis of trehalose conjugates. He then joined Dr. Ramu Sridhar’s lab at the University of Hyderabad for his doctoral studies. In 2015, he received a Ph.D. degree in Chemistry where he developed synthetic methodologies in the construction of bioactive skeletons and natural products using 3-C branched glycals. In 2016, he joined Dr. Peng George Wang’s lab at Georgia State University as a postdoctoral research associate and mainly worked on the synthesis of lipopolysaccharide (LPS) and O-glycans. He developed synthetic methodologies in the chemoenzymatic construction of complex glycans . In 2019, he joined Dr. Lei Li’s group and was later promoted as a research scientist at Georgia State University. His current research interests include developing novel synthetic methodologies in the synthesis of LPS, natural complex carbohydrates and glycoconjugates, and developing vaccines and carbohydrate-based therapeutics.
Dr. Jinghua Han
Postdoctoral Fellow in Carbohydrate Chemistry
Email:
Dr. Han graduated from Taishan Medical University in 2009, earning a B.S. degree in Pharmacy. Then he received his M.S. degree in Medicinal Chemistry at Nankai University in 2013 and finished his Ph.D. study in Chemical Biology at Nankai University in 2018. He then joined Department of Chemistry at Georgia State University. Currently, his research focuses on the chemoenzymatic synthesis of Glycans and Glyco-macromolecules.
Dr. Shuaishuai Wang
Postdoctoral Research Associate in Functional Glycomics and Chemical Biology
Email:
Dr. Wang obtained his B.E. in Pharmaceutical Engineering from Southwest University (China) in 2012, and M.S. in Biochemistry and Molecular Biology from Shandong University (China) in 2015. He started his Ph.D. study at the Georgia State University in 2016 and earned his Ph.D. degree in the middle of 2020. His graduate research focused on the synthesis of mammalian glycans and glycopeptides. In the same year, he joined Lei Li's group to continue his research in the field of glycomics and glycobiology.
Dr. Ding Liu
Postdoctoral Fellow in Glycomics and Chemical Biology
Email:
Dr. Ding Liu graduated from Hubei University of Chinese Medicine in China in 2015 with a Bachelor of Medicine. He was trained in a Clinical Lab in Hubei People’s Hospital from 2013 to 2014. After that, he joined Dr. Peng George Wang’s group at Georgia State University as a master student. During 2015-2016, he mainly worked on large scale synthesis of oligosaccharide building blocks. From 2016, Ding was transferred to Ph.D. program in the same lab and obtained Ph.D. degree in Analytical Chemistry in 2020. In the same year, Ding joined Dr. Lei Li’s lab as postdoc fellow, his research mainly focus on glycomics and proteomics study of hemophilia and cancer based on Mass Spectrometry.
Past Members
Dr. Arya Aloor
Postdoctoral Fellow in Glycomics