Principal Investigator

20200910MLB_Lei_Li_PSFS_edited_edited.jp

Dr. Lei Li

Assistant Professor

Department of Chemistry

Georgia State University

Office Phone: (404) 413-5073

Office Address: 50 Decatur ST SE

Email: lli22@gsu.edu

Dr. Lei Li graduated from Shandong University in China in 2005 with a B.S. degree in Biotechnology. He then received his Ph.D. degree in Microbiology in State Key Laboratory of Microbial Technology at Shandong University in 2010. During the Ph.D. program, he joined Dr. Peng George Wang's group at The Ohio State University as a visiting scholar from 2007 to 2009, where he worked on elucidating the biosynthetic pathway of lipopolysaccharides and synthesis of biomedical-related glycans. He then spent two years at Nankai University as a Postdoctoral Associate, focusing on chemoenzymatic synthesis of complex glycans and sugar nucleotides. In 2013, he joined Dr. Peng George Wang's lab at Georgia State University as Research Scientist I and was promoted to Senior Research Scientist in 2018. He developed independent research programs in microbial glycobiology and glycomics under the support of NIH. In 2020, he joined Department of Chemistry as an Assistant Professor. His research interest includes expedited synthesis of complex carbohydrates and glycoconjugates, glycomics tools (glycan microarray and mass spectrometry) to profile cell-surface glycans and elucidate glycan-protein interactions, as well as carbohydrate-related vaccines and therapeutics against antibiotic-resistant bacteria.  

CURRENT MEMBER

Dr. Madhusudhan Reddy Gadi

Research Scientist in Carbohydrate Chemistry

Dr. Gadi obtained a master’s degree in Chemistry from the University of Hyderabad in 2009 where he worked on the isolation of natural products and chemical synthesis of trehalose conjugates. He then joined Dr. Ramu Sridhar’s lab at the University of Hyderabad for his doctoral studies. In 2015, he received a Ph.D. degree in Chemistry where he developed synthetic methodologies in the construction of bioactive skeletons and natural products using 3-C branched glycals. In 2016, he joined Dr. Peng George Wang’s lab at Georgia State University as a postdoctoral research associate and mainly worked on the synthesis of lipopolysaccharide (LPS) and O-glycans. He developed synthetic methodologies in the chemoenzymatic construction of complex glycans . In 2019, he joined Dr. Lei Li’s group and was later promoted as a research scientist at Georgia State University. His current research interests include developing novel synthetic methodologies in the synthesis of LPS, natural complex carbohydrates and glycoconjugates, and developing vaccines and carbohydrate-based therapeutics.

Dr. Jinghua Han

Postdoctoral Fellow in Carbohydrate Chemistry

Dr. Han graduated from Taishan Medical University in 2009, earning a B.S. degree in Pharmacy. Then he received his M.S. degree in Medicinal Chemistry at Nankai University in 2013 and finished his Ph.D. study in Chemical Biology at Nankai University in 2018. He then joined Department of Chemistry at Georgia State University. Currently, his research focuses on the chemoenzymatic synthesis of glycopeptides and bacterial polysaccharides.

Dr. Shuaishuai Wang

Postdoctoral Research Associate in Functional Glycomics and Chemical Biology

Dr. Wang obtained his B.E. in Pharmaceutical Engineering from Southwest University (China) in 2012, and M.S. in Biochemistry and Molecular Biology from Shandong University (China) in 2015. He started his Ph.D. study at the Georgia State University in 2016 and earned his Ph.D. degree in the middle of 2020. His graduate research focused on the synthesis of mammalian glycans and glycopeptides. In the same year, he joined Lei Li's group to continue his research in the field of glycomics and glycobiology.

Dr. Congcong Chen

Postdoctoral Fellow in Functional Glycomics and Chemical Biology

 

Dr. Chen obtained her B.E. in Pharmaceutical Engineering from Shandong University of Traditional Chinese Medicine in 2012, then she got her master’s degree and Ph.D. degree in Microbial and Biochemical Pharmacy from Shandong University in 2015 and 2020. During her graduate studies, she focused on the chemoenzymatic synthesis of human milk oligosaccharides and poly-LacNAc oligosaccharides. Her current research interests include novel chemo-enzymatic methods for the assembly of oligosaccharides.

Deepti Singh

Visiting Scholar

Deepti obtained her graduation and post-graduation degree from Dr. R M L Awadh university Faizabad UP, India. In 2018, she joined Indian Institute Of Technology Kanpur UP (India) as a Ph.D. Student, working on biodegradation of environmental toxic aromatic micropollutants by enzymatic catalytic reactions. Deepti joined the group as a visiting scholar on Sep. 2021, focusing on length-controlled chemoenzymatic synthesis of bacterial Polysaccharide 

Avinash Ittuveetil

Ph.D Student, Carbohydrate Chemistry

Avinash obtained his bachelor's degree in pharmacy from the College of  Pharmaceutical Sciences, Govt. Medical College, Calicut. He obtained his Masters's degree (Thesis) in medicinal chemistry from the National Institute of pharmaceutical education and research, Mohali, India. Avinash joined the group as a Ph.D. student on Sep. 2021.

Shumin Bao

Ph.D Student, Glycobiology and Chemical Biology
 

Bao obtained her Bachelor’s degree in Pharmacy from Qinghai University and Master’s degree from Central South University. She joined the group as a Ph.D. student on Jan. 2022.

Tangliang Shen

Ph.D Student, Carbohydrate Chemistry

Shen obtained his Bachelor's degree of Engineering in Pharmaceutical Engineering from Anhui University of Chinese Medicine in 2017, and Master's degree Engineering in Pharmaceutical Engineering from in Nankai University in 2020. He joined the group as a Ph.D. student on Jan. 2022.

ALUMINI

Dr. Ding Liu

2020.7 - 2021.9           Postdoctoral Fellow in Glycomics & Chemical Biology

Current Position          Scientist at Moderna

Dr. Arya Aloor

2020.6-2020.8              Postdoctoral Fellow in Glycomics

Current Position           Senior Research Scientist at Amrita School of Biotechnology, India